Fig. 1

Endoscopic image of original tumor, morphological and immunofluorescence staining photos of derived cancer cells. a Endoscopic photograph of the original tumor. b–e, Morphology of CSEC216 cells at P0. f, Cytokeratin positively expressed on cytomembrane with red color. g, e-cadherin positively expressed on cytomembrane with red color. h Vimentin negatively expressed. i Ki-67 positively expressed in nuclear with red color