Table 1 Characteristics of the included studies
From: Long noncoding RNAs as potential biomarkers in retinoblastoma: a systematic review and meta-analysis
First author | Year | LncRNA | Expression | Sample size | Cut-off value | PT | Survival | Survival analysis | HR availability | NOS score |
|---|---|---|---|---|---|---|---|---|---|---|
Xue-Zhi Wu | 2019 | PVT1 | Upregulated | 78 retinoblastoma tissue specimens 30 normal retina samples | Median | No | OS | U | Kaplan–Meier | 8 |
Fengqin Hao | 2018 | AFAP1-AS1 | Upregulated | 58 retinoblastoma tissue specimens 10 non-cancerous retina tissue specimens | Median | No | OS | U, M | Kaplan–Meier | 8 |
Ge Yang | 2018 | HOTAIR | Upregulated | 350 eyes were collected from 276 patients | NA | No | OS | U, M | Kaplan–Meier | 5 |
Shizheng Su | 2015 | BANCR | Upregulated | 60 retinoblastoma samples 4 normal retina samples | Median | NA | OS | U, M | Kaplan–Meier | 7 |
Li Li | 2016 | H19 | Upregulated | 80 retinoblastoma tissue samples | NA | No | OS | U, M | NA | 5 |
Jingxian Wang | 2018 | DANCR | Upregulated | 57 cases of RB patients and matched health controls | NA | NA | OS, DFS | U | Kaplan–Meier | 8 |
Guigang Yan | 2019 | LINC00202 | Upregulated | 50 cases of RB tissues and paired normal tissues | Fold change | NA | OS, DFS | U | Kaplan–Meier | 8 |
L.-L. Bi | 2018 | MT1JP | Downregulated | 44 retinoblastoma tissues and matched non-tumor tissues | Median | No | OS | M | Kaplan–Meier | 8 |
Weiwei Shang | 2018 | BDNF-AS | Downregulated | 131 patients with RB 35 normal retinal specimens | Median | NA | OS | U, M | Kaplan–Meier | 8 |