Fig. 3
From: Knockdown of LINC00662 represses AK4 and attenuates radioresistance of oral squamous cell carcinoma
hnRNPC bound with AK4 mRNA to stabilize AK4 mRNA. a The putative binding capacity between hnRNPC and AK4 was predicted from starBase. b, c The combination of hnRNPC with AK4 was confirmed by RIP and western blot assays. d qRT-PCR and western blot evaluated hnRNPC expression in sh-hnRNPC transfected CAL27 and SCC-4 cells. e qRT-PCR detection of AK4 level in CAL27 and SCC-4 cells with the transfection of sh-hnRNPC. f Under actinomycin D treatment, the mRNA stability of AK4 was assessed through qRT-PCR by knockdown of hnRNPC. g qRT-PCR and western blot evaluated hnRNPC expression in hnRNPC-KO transfected CAL27 and SCC-4 cells. h qRT-PCR revealed AK4 expression by knockout of hnRNPC. i Under actinomycin D treatment, the mRNA stability of AK4 was assessed through qRT-PCR by knockout of hnRNPC. **P < 0.01