Fig. 6
From: Knockdown of LINC00662 represses AK4 and attenuates radioresistance of oral squamous cell carcinoma
LINC00662 promoted the radiosensitivity of OSCC cells via AK4. a CCK-8 experiment evaluated cell proliferation of CAL27 and SCC-4 cells under 4Gy irradiation with AK4 overexpression to rescue silenced LINC00662. b In colony formation assay, survival fraction of CAL27 and SCC-4 cells was determined at the indicated doses of 0, 2, 4 and 8Gy irradiation with AK4 overexpression to rescue silenced LINC00662. c Flow cytometry result of cell apoptosis in CAL27 and SCC-4 cells with AK4 overexpression to rescue silenced LINC00662. d Protein levels of cleaved PARP, cleaved caspase-3, total PARP and caspase-3 in CAL27 and SCC-4 cells were examined through western blot with AK4 overexpression to rescue silenced LINC00662. *P < 0.05 and **P < 0.01