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Fig. 3 | Cancer Cell International

Fig. 3

From: Matrine inhibits cell growth, migration, invasion and promotes autophagy in hepatocellular carcinoma by regulation of circ_0027345/miR-345-5p/HOXD3 axis

Fig. 3

Circ_0027345 was a sponge of miR-345-5p in HCC cells. a The binding sites between circ_0027345 and miR-345-5p, and wild-type and mutant of circ_0027345 were displayed. b, c Dual luciferase reporter assay was performed to clarify the interaction between circ_0027345 and miR-345-5p. d, e The expression of miR-345-5p in Huh-7 and HCCLM3 cells transfected with pcDNA-NC or pcDNA-circ_0027345 was determined by qRT-PCR. f, g The expression of miR-345-5p in Huh-7 and HCCLM3 cells treated with various concentrations of matrine was examined by qRT-PCR. *P < 0.05

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Cancer Cell International

ISSN: 1475-2867

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