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Fig. 8 | Cancer Cell International

Fig. 8

From: Downexpression of HSD17B6 correlates with clinical prognosis and tumor immune infiltrates in hepatocellular carcinoma

Fig. 8

The methylation status of HSD17B6 promoter is dependent on E2F6. a, b Correlation of HSD17B6 expression with E2F6 expression in TCGA-LIHC dataset. c E2F6 binds to the promoter region of HSD17B6. Re-analysis of six different E2F6 ChIP-seq data available in CistromeDB platform. E2F6 chromatin immunoprecipitation was performed in four different human cancer-derived cell lines: A549 (lung carcinoma), H1 (embryonic stem cell), HeLa-S3 (cervical adenocarcinoma) and K562 (chronic myelogenous leukemia, including 3 ChIP-seq datasets from different research), and the presence of DNA peaks was evaluated in HSD17B6 promoter regions

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