Fig. 3
From: LINC01094 triggers radio-resistance in clear cell renal cell carcinoma via miR-577/CHEK2/FOXM1 axis
Cytoplasmic LINC01094 was an endogenous sponge of miR-577 in ccRCC. a lncLocator prediction of LINC01094 localization. b The specific distribution of LINC01094 in Caski and 786-O cells was determined via subcellular fractionation and qRT-PCR. c The expression of miR-577 in these ccRCC cell lines was tested by qRT-PCR. d qRT-PCR result of miR-577 level in Caski and 786-O cells with or without LINC01094 inhibition. e The expression of miR-577 or LINC01094 in Caski and 786-O cells with the transfection of miR-NC or miR-577 mimics was analyzed by qRT-PCR. f, g The binding sequences and results of luciferase reporter assay in HEK-293T cells. h RIP assay uncovered the co-enrichment of LINC01094 and miR-577 in Ago2-assembled RISC in two ccRCC cells. *P < 0.05, **P < 0.01, ***P < 0.001