Fig. 1

Circ_LDLR level was elevated in PTC tissues and cells. a Circ_LDLR was upregulated in PTC according to the analysis of GEO dataset GSE93522. b, c The expression level of circ_LDLR in PTC tissues (N = 60), cells and corresponding normal tissues and cells was determined using qRT-PCR (Student’s t-test). d, e The expression levels of circ_LDLR and LDLR were measured by qRT-PCR after treatment with or without RNase R in TPC-1 and SW579 cells. f, g The expression levels of circ_LDLR and LDLR were examined using qRT-PCR after treatment with Actinomycin D at indicated time points in TPC-1 and SW579 cells. *P < 0.05. Each bar represents mean ± SD