Fig. 1

Identification of methylation-driven genes in pRCC. a Heat map of methylation-driven genes in pRCC. The color from green to red shows a trend from hypomethylation to hypermethylation. b–e The correlation between methylation and gene expression in methylation-driven genes. f–i The methylation degree when comparing cancer samples to normal samples in pRCC. The histogram represents the distribution of methylation in tumor samples. The black line above the figure demonstrates the distribution of methylation levels in normal samples