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Fig. 2 | Cancer Cell International

Fig. 2

From: LncRNA LINC00261 overexpression suppresses the growth and metastasis of lung cancer via regulating miR-1269a/FOXO1 axis

Fig. 2

LINC00261 overexpression suppressed the growth of LC cells. a, b The efficiency of LINC00261 overexpression in A549 (a) and SPC-A1 (b) was measured by qRT-PCR, 72 h after infection. (c, d) The viabilities of A549 (c) and SPC-A1 (d) cells after infection for 24 h, 48 h and 72 h were measured by CCK-8 assay. (eg) The colony formation abilities of A549 (f) and SPC-A1 (g) cells after infection were determined by colony formation assay. (hk) Cells were harvested 2 weeks after infection and the levels of Ki-67, PCNA in A549 (hi) and SPC-A1 (j, k) cells were determined by Western blot. GAPDH served as an internal control. *P < 0.05, **P < 0.001 vs. blank, #P < 0.05, ##P < 0.001 vs. NC. Blank: untreated cells. NC: pCDH-CMV empty plasmid. LINC00261: pCDH-CMV- LINC00261 overexpression plasmid. All experiments repeated independently in triplicate

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