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Fig. 8 | Cancer Cell International

Fig. 8

From: LncRNA LINC00261 overexpression suppresses the growth and metastasis of lung cancer via regulating miR-1269a/FOXO1 axis

Fig. 8

MiR-1269a promoted the growth of LC cells through targeting FOXO1. a, b The level of FOXO1 in A549 (a) and SPC-A1 (b) cells was measured by qRT-PCR. c, d The viabilities of A549 (c) and SPC-A1 (d) cells after infection were measured by CCK-8 assay. eg The colony formation abilities of A549 (f) and SPC-A1 (g) cells after infection were determined by colony formation assay. *P < 0.05, **P < 0.001, vs Vector. #P < 0.05, ##P < 0.05 vs. FOXO1. ^P < 0.05, ^^P < 0.05 vs. mimic. Vector: pCDH-CMV empty plasmid. FOXO1: pCDH-CMV-FOXO1 overexpression plasmid. Mimic: miR-1269a mimic. FOXO1 + mimic: pCDH-CMV-FOXO1 and miR-1269a mimic. All experiments repeated independently in triplicate

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