Table 3 Correlation of clinicopathological characteristics with HPV presence
Degree of differentiation | HPV (E6) positive (%) | HPV (E6) negative (%) | p-value |
|---|---|---|---|
Tumor grade | |||
Well-differentiated | 6 (8.6) | 9 (13) | p = 0.02* |
Moderately-differentiated | 23 (33.3) | 20 (28.9) | |
Poorly-differentiated | 10 (14.4) | 1 (1.4) | |
Total | 39 (56.5) | 30 (43.4) | |
Tumor Stage (pT) | |||
pT1 | 3 (4.4) | 14 (20.8) | p < 0.001* |
pT2 | 10 (14.9) | 12 (17.9) | |
pT3 | 13 (19.4) | 2 (2.9) | |
pT4 | 10 (14.9) | 3 (4.4) | |
Total | 36 (53.7) | 31 (46.2) | |
pN Stage | |||
pN0 | 11 (29.7) | 8 (21.6) | p = 0.045* |
pN1 | 8 (21.6) | 2 (5.4) | |
pN2 | 7 (18.9) | 1 (2.7) | |
Total | 26 (70.2) | 11 (29.7) | |