Fig. 2
From: Palbociclib treatment alters nucleotide biosynthesis and glutamine dependency in A549 cells
Palbociclib does not alter glucose carbon incorporation into glycolytic intermediates in A549 cells. a Cartoon of [U-13C]-glucose fate mapping though glycolysis. Red circles indicate 13C. Fractional enrichment of m + 6 labeled b glucose 6-phosphate and c fructose 6-phosphate, and m + 3 labeled d 3-phosphoglycerate, e phosphoenolpyruvate, f pyruvate, and g lactate following 48-h treatment with 1 μM palbociclib. Values represent mean ± SD, analyzed by unpaired student’s t-test (n = 6, technical replicates)