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Fig. 2 | Cancer Cell International

Fig. 2

From: Long non-coding RNA NORAD exhaustion represses prostate cancer progression through inhibiting TRIP13 expression via competitively binding to miR-495-3p

Fig. 2

Effects of NORAD downregulation on the proliferation, apoptosis, migration and invasion of PCa cells. a The expression of NORAD in 22Rv1 and LNCaP cells was evaluated by qRT-PCR. a–j 22Rv1 and LNCaP cells were transfected with si-NC or si-NORAD. b, c MTT assay was executed for the detection of the proliferation of 22Rv1 and LNCaP cells. d Flow cytometry assay was performed to assess the apoptosis of 22Rv1 and LNCaP cells. e–h Western blot analysis was conducted for the assessment of the levels of Bax, Bcl-2, and Cleaved-casp-3 in 22Rv1 and LNCaP cells. i, j Transwell assay was employed to evaluate the migration and invasion capacities of 22Rv1 and LNCaP cells. The experiments were performed in triplicate. ***P < 0.001

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Cancer Cell International

ISSN: 1475-2867

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