Fig. 5
From: SUV39H1-DNMT3A-mediated epigenetic regulation of Tim-3 and galectin-9 in the cervical cancer
SUV39H1 changed HAVCR2 and LGALS9 methylation level in cervical cancer cells. a, c The methylation level of HAVCR2 and LGALS9 promoter regions were monitored by MS-PCR in SUV39H1 overexpressed and knocked-down SiHa and HeLa cells (M methylated, U unmethylated). b, d Methylated and unmethylated levels were quantified as M/M + U% and U/M + U%, respectively. e, f Western blotting analysis of SiHa and HeLa cells overexpressed and knocked-down SUV39H1 against Tim-3 and galectin-9. *P < 0.05, **P < 0.01