Fig. 5

miR-138-5p inhibited tumorigenic ability in nude mice. a, b Tumor volume growth curves were calculated for different nude mice after injection of NC mimic and miR-138-5p mimic, respectively; c Tumor weight growth curves were calculated after injection of NC mimic and miR-138-5p mimic, respectively; d qRT-PCR was used to detect the expression level of miR-138-5p in the tumor-forming tissues of nude mice; e Western Blotting was used to detect the expression level of FZD4 in the tumor-forming tissues of nude mice; f Immunohistochemistry was used to detect the expression level of FZD4 in the tumor-forming tissues of nude mice with Hep3B cell line (magnification: 40×). Data are mean ± SD, *p < 0.05, **p < 0.01