Fig. 1

DEGs between ICC tissues and adjacent normal tissues were identified. a The heat map of DElncRNAs. The x-axis represents the sample, and the y-axis represents a DElncRNAs. Red represents upregulated DElncRNAs and green represents downregulated DElncRNAs. b The volcano plot of DElncRNAs. The y-axis represents the negative base-10 logarithm of the corrected p value, and the x-axis represents the base-2 logarithm of FC. Each point represents a DElncRNA. Green dots indicate downregulated DElncRNAs, red dots indicate upregulated DElncRNAs, and black dots indicate lncRNAs that are not differentially expressed. c DElncRNAs determined by principal component analysis. Adjacent normal tissues (red, n = 27) and ICC tissues (green, n = 30) were plotted along the axis around the first two main components (PC1 and PC2). d The heat map of DEmiRs. The x-axis represents the sample, and the y-axis represents DEmiRs. Red represents upregulated DEmiRs and green represents downregulated DEmiRs. e The volcano plot of DEmiRs. The y-axis represents the negative base-10 logarithm of FDR, and the x-axis represents the base-2 logarithm of FC, and each point represents a DEmiR. Green dots indicate downregulated DEmiRs, red dots indicate upregulated DEmiRs, and black dots indicate miRs that are not differentially expressed. f The heat map of DEmiRs. The y-axis represents the sample, and the y-axis represents DEmiRs. Red represents upregulated DEmiRs and green represents downregulated DEmiRs. g The volcano plot of DEmRNAs. The y-axis represents the negative base-10 logarithm of FDR, the x-axis represents the base-2 logarithm of FC. Each dot represents a DEmRNA. Green dots indicate downregulated DEmRNAs, red dots indicate upregulated DEmRNAs, and black dots indicate mRNAs that are not differentially expressed