Fig. 6
From: Circ_0000527 promotes the progression of retinoblastoma by regulating miR-646/LRP6 axis
Regulatory effect of circ_0000527/miR-646 axis on the expression of LRP6. a The binding site between miR-646 and the 3′UTR of LRP6. b The binding relationship between miR-646 and 3′UTR of LRP6 was verified by luciferase activity assay. c The expression of LRP6 was detected by qRT-PCR and Western blot after up-regulation or down-regulation of cric_0000527, respectively. d The expression of LRP6 was detected by qRT-PCR and Western blot after up-regulation or inhibition of miR-646, respectively. ***P < 0.001, and **P < 0.01