Fig. 8
From: Long noncoding RNA HOTAIR promotes breast cancer development by targeting ZEB1 via sponging miR-601
HOTAIR interference attenuated BC tumor growth in vivo. a Tumor volume of the sh-HOTAIR group was smaller than that of the control or sh-NC group. b Tumor weight was remarkably reduced in the sh-HOTAIR group compared with the control and sh-NC group. c The HOTAIR expression in tumor tissues was detected by qRT-PCR. d QRT-PCR analysis revealed that miR-601 expression in the tumor tissues of the sh-HOTAIR group was markedly higher than that in the control or sh-NC group. e WB assay revealed that ZEB1 protein expression in the tumor tissues of the sh-HOTAIR group was significantly lower than that in the control and sh-NC group. f IHC assay results revealed that Ki-67 expression was decreased in the sh-HOTAIR group. g, h The protein levels of Ki-67 and p-AKT/AKT were tested using WB analysis. *P < 0.05