Fig. 6

Inhibitor for miR-345-3p or overexpression of VAMP8 could rescue the cell viability and cell Colony formation caused byLINC01426 absence. a The miR-345-3p expression level was dramatically decreased in U251 stable cell line when treated with miR345-3p inhibitors. b qRT-PCR showed the overexpression efficiency of VAMP8 in the U251 cell with LINC01426 knockdown. c CCK8 assay showed miR345-3p inhibitors and ectopic expression of VAMP8 could rescue the impaired viability caused by LINC01426 knockdown. c Colony formation assay showed both miR345-3p inhibitors and ectopic expression of VAMP8 could rescue the inhibitory effect on the ability of Colony formation with LINC01426 knockdown. All of the data are represented as mean ± SD of three times