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Fig. 6 | Cancer Cell International

Fig. 6

From: Circular RNA ITCH suppresses proliferation, invasion, and glycolysis of ovarian cancer cells by up-regulating CDH1 via sponging miR-106a

Fig. 6

miR-106a knockdown inhibited cell progression in ovarian cancer by targeting CDHI. a The protein level of CDH1 in A2780 and OVCAR3 cells transfected with anti-miR-con, anti-miR-106a, anti-miR-106a + si-con or anti-miR-106a + si-CDH1 was measured by western blot. b The proliferation of A2780 and OVCAR3 cells was detected by CCK-8 assay. c The invasion of A2780 and OVCAR3 cells was assessed by Transwell assay with Matrigel. df Glucose consumption, lactate production and ATP level in A2780 and OVCAR3 cells were assessed using glucose, lactate and ATP assay kits, respectively. g The apoptosis of A2780 and OVCAR3 cells was analyzed by Flow cytometry. *P < 0.05, **P < 0.01, ***P < 0.001

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