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Fig. 1 | Cancer Cell International

Fig. 1

From: Targeting deubiquitinating enzyme USP26 by microRNA-203 regulates Snail1’s pro-metastatic functions in esophageal cancer

Fig. 1

SNAI1 is upregulated and hsa-miR-203 is downregulated in esophageal cancer.  Fold-change (log2) of SNAI1 (a) and USP26 (b) in esophageal cancer tumor tissue compared to tumor adjacent normal tissues. Data in a and b are from 1687 patients from TCGA analyzed by the cBioPortal. c, d Expression profile of miR-203 analyzed from non-coding RNA profiling array data downloaded from GEO by GEO2R. Shown are log2 converted expression in 119 paired samples obtained from GSE43732 (c), robust multiarray analysis (RMA) raw values in 104 tumor-adjacent normal tissue and 153 esophageal tumor tissue in GSE6188. (Fig. 1d; P < 0.0001). Shown are scatter plots, mean with range; ****P < 0.0001

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