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Fig. 6 | Cancer Cell International

Fig. 6

From: Circular RNA circ_0020123 promotes non-small cell lung cancer progression by sponging miR-590-5p to regulate THBS2

Fig. 6

Overexpression of THBS2 reversed the effects of circ_0020123 knockdown on proliferation, migration and apoptosis of NSCLC cells. a, b The mRNA and protein expression of THBS2 in A549 and H1299 cells transfected with pcDNA3.1-THBS2 was detected by qRT-PCR and Western blot. c CCK-8 assay indicated the proliferation of A549 and H1299 cells transfected with si-circ_0020123-1 or si-circ_0020123-1 + pcDNA3.1-THBS2. d The migration of A549 and H1299 cells transfected with si-circ_0020123-1 or si-circ_0020123-1 + pcDNA3.1-THBS2 was measured by Transwell assay. e The apoptosis of A549 and H1299 cells transfected with si-circ_0020123-1 or si-circ_0020123-1 + pcDNA3.1-THBS2 was detected by Flow cytolysis assay. f The protein levels of Ki-67, MMP-9, Cleaved-casp9 in A549 and H1299 cells transfected with si-circ_0020123-1 or si-circ_0020123-1 + pcDNA3.1-THBS2 were detected by Western blot. *P < 0.05

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Cancer Cell International

ISSN: 1475-2867

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