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Fig. 3 | Cancer Cell International

Fig. 3

From: CircHIPK3/miR-876-5p/PIK3R1 axis regulates regulation proliferation, migration, invasion, and glutaminolysis in gastric cancer cells

Fig. 3

MiR-876-5p was a target of circHIPK3. a The binding sites of wild type circHIPK3 in miR-876-5p were shown. b, c The relative luciferase activity was assessed in HGC-27 and AGS cells by dual-luciferase report assay. d, e RT-qPCR assay was applied to analyze the expression level of miR-876-5p in HGC-27 and AGS cells transfected with si-NC or si-circHIPK3. f, g The expression level of miR-876-5p was examined by RT-qPCR assay in gastric cancer tissues and cells, along with matched control groups. h The correlation relationship between miR-876-5p and circHIPK3 was analyzed by Pearson’s correlation analysis in gastric cancer tissues. *P < 0.05

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