Fig. 6From: Evaluation of the upregulation and surface expression of hypoxanthine guanine phosphoribosyltransferase in acute lymphoblastic leukemia and Burkitt’s B cell lymphomaALL patients show elevated surface HPRT. Patient samples were stained with PI to discriminate against dead cells. APC conjugated secondary antibodies were used in conjunction with protein-specific primary antibodies to stain proteins of interest. Upon evaluation of 9 ALL patient samples, we found that 7 of them had elevated HPRT surface localization with an average fluorescent population shift of 25%. This indicates that the surface localization observed in Raji cells is also found within patientsBack to article page