Fig. 4

Tan IIA inhibits cell growth via blocking AKT3 by miR497-5p. a HL-60 cells were transfected with miR-497-5p inhibitor and then treated with Tan IIA or not. Cell proliferation was examined by the CCK-8 assay. b HL-60 cells were treated as (a), cell apoptosis was examined by Annexin V and PI staining. c HL-60 cells were treated as (a), the protein expression levels of PCNA, cleaved Caspase-3, p-AKT and AKT3 was examined by western blot analysis