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Fig. 6 | Cancer Cell International

Fig. 6

From: A novel mechanism by which ACTA2-AS1 promotes cervical cancer progression: acting as a ceRNA of miR-143-3p to regulate SMAD3 expression

Fig. 6

The effect of ACTA2-AS1/miR-143-3p/SMAD3 axis on progression of CC. a The knock-down ability of si-SMAD3 in HeLa and SiHa cells was confirmed by qRT-PCR. b The over-expression ability of pcDNA-ACTA2-AS1 was confirmed by qRT-PCR. c Cell viability was detected by CCK8 assay after transfecting with si-SMAD3 and co-transfecting with pcDNA‐ACTA2‐AS1 or miR-143-3p inhibitor. d The migration ability of transfected cells was analyzed by transwell assay. e Apoptosis condition of transfected cells was analyzed by flow cytometry analysis. ** P < 0.01, *P < 0.05

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Cancer Cell International

ISSN: 1475-2867

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