Fig. 1

LINC00261 binds to the transcription factor GATA6 to regulate DKK3. a The Volcano map of expression of DEGs in prostate cancer. LogFC is represented on the x axis and log10 p value on the y axis. Each point in the graph represents a gene, red dot represents an up-regulated gene, green dot represents a down-regulated gene. b The expression of LINC00261 in prostate cancer tissues and normal samples in TCGA database, The x axis indicates the disease name and the number of samples, the y axis indicates the expression value, the red box graph represents the tumor sample, and the gray box graph represents the normal sample. c The relationship among lncRNA, transcription factor and gene. d The intersection of genes in LncMap database and DEGs in microarray GSE45016. The circle on the left represents the prediction results of the LncMap database, the circle on the right represents the differential genes in the new product, and the middle part represents the intersection of the two sets of data. e The expression of DKK3 in prostate cancer and normal tissues assayed by RT-qPCR, *p < 0.05 vs. the normal tissues, **p < 0.01 vs. the normal tissues. f The expression of DKK3 in prostate cancer and normal tissues in TCGA database. The x axis indicates the disease name and the number of samples, the y axis indicates the expression value, the red box graph represents the tumor sample, and the gray box graph represents the normal sample