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Fig. 3 | Cancer Cell International

Fig. 3

From: Cryptotanshinone chemosensitivity potentiation by TW-37 in human oral cancer cell lines by targeting STAT3–Mcl-1 signaling

Fig. 3

Ectopic expression of Mcl-1 attenuates TW-37-induced apoptosis. HSC-3 cell lines were treated with DMSO or 5-μM TW-37 for 48 h after transiently transfected with 0.5-μg pcDNA3.1 or pcDNA3.1-Mcl-1 for 6 h. a Protein levels of myeloid cell leukemia-1 (Mcl-1) and cleaved PARP were determined using Western blotting. Actin was used as a loading control. b FACS analysis of annexin V/PI staining. All bar graphs represent mean ± SD of three independent experiments. *P < 0.05; #P < 0.05

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Cancer Cell International

ISSN: 1475-2867

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