Fig. 3

The relationship between circ_0000517 and miR-326. a The targets of circ_0000517 were analyzed via circBank, StarBase and circinteractome. b, c miR-1296 and miR-326 levels were detected in HCCLM3, Huh7 and THLE-2 cells with transfection of si-circ_0000517#3 or si-NC. d The binding site of circ_0000517 and miR-326. e, f Luciferase activity was examined in HCCLM3 and Huh7 cells transfected with circ_0000517-WT or circ_0000517-MUT and miR-326 mimic or miR-NC. g miR-326 expression was measured in tumor and adjacent nontumor tissues from patients with hepatocellular carcinoma. h miR-326 level was examined in HCCLM3, Huh7 and THLE-2 cells. i The relationship between miR-326 and circ_0000517 levels in hepatocellular carcinoma tissues. ^*P < 0.05