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Fig. 2 | Cancer Cell International

Fig. 2

From: XIST lost induces ovarian cancer stem cells to acquire taxol resistance via a KMT2C-dependent way

Fig. 2

XIST up-regulated KMT2C expression by stabilizing its mRNA. a XIST expression was associated with methylation of histone 3. b XIST regulated KMT2C expression levels. c XIST did not regulate the stability of the KMT2C protein. d XIST increased the stability of KMT2C mRNA. e XIST regulated KMT2C mRNA stability by its 3-UTR. *: compared with SKOV3, #: compared with TOV21G. *p < 0.05, **p < 0.01, ***p < 0.001; # p < 0.05, ## p < 0.01, ### p < 0.001

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