Fig. 6
From: Development of syngeneic murine cell lines for use in immunocompetent orthotopic lung cancer models
Validation of a Pik3ca+.p53+/− cell line. a H&E stain showing orthotopic tumor formation by line Y856. Scale bar is 100 µm and the red line denotes the tumor border. b PCR of genomic DNA showing recombination of the R26StopFLP110* allele (242 bp) and Tp53 allele (612 bp) in Y856 cells. c Western blot showing increased pAKT expression and reduced TP53 expression in Y856 cells