Fig. 4
From: MicroRNA-214-3p inhibits the stem-like properties of lung squamous cell cancer by targeting YAP1
MiR-214 overexpression impairs LSCC tumor initiation and progression of orthotropic models. a Images of primary tumors in the left lungs at day 21 from each group after injection of H520 cells transfected with miR-214-3p mimics and NC mimics. b and c Mean primary tumor volume and body weight from two groups. (Error bars represent SEM; *p < 0.05). d Survival for the mice in each group evaluated. **p < 0.01. e–g Upper panel: Representative IF images of YAP1 and stem-related biomarkers, including SOX2 and CD133. Lower panel: Quantification of biomarker expression (Error bars represent SEM, N = 6; *p < 0.05; ** P < 0.01)