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Fig. 1 | Cancer Cell International

Fig. 1

From: CircUBE2D2 (hsa_circ_0005728) promotes cell proliferation, metastasis and chemoresistance in triple-negative breast cancer by regulating miR-512-3p/CDCA3 axis

Fig. 1

CircUBE2D2 is frequently increased and indicates a poor prognosis in TNBC. (a and b) Relative expression of circUBE2D2 in TNBC tissues (Tumor) and adjacent non-cancerous tissues (Normal) was determined by qRT-PCR. c Relative expression of circUBE2D2 in tumor tissues at different TNM stages. d Relative expression of circUBE2D2 in tumor tissues with or without lymph node metastasis. e Kaplan–Meier method was used to determine the correlation between circUBE2D2 expression and overall survival of TNBC patients. The median expression of circUBE2D2 was set as a cut-off value to divide patients into high expression group and low expression group. f Relative expression of circUBE2D2 in five TNBC cells and one normal mammary epithelial cell. *P < 0.05, **P < 0.01, ***P < 0.001

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Cancer Cell International

ISSN: 1475-2867

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