Fig. 3

Overexpression of miR-367 suppresses proliferation, invasion, and angiogenesis of ovarian cancer A2780 cells. a RT-qPCR detection on miR-367 vectors transfection efficiency. b The proliferation of A2780 cells (scale bar = 25 μm) measured by EdU assay. c Ovarian cancer cell proliferation rate statistics. d The invasive ability of A2780 cells detected by Transwell assay (scale bar = 50 μm). e Statistical graph of A2780 cell invasion and relative cell number. f Representative image of tube formation (scale bar = 100 μm). g Statistics of relative length of blood vessels. h Relative number of blood vessel branches. i CAM blood flow statistics. j CAM blood vessel area statistics. k CAM blood vessel area ratio chart. l CAM tissue area chart. m RT-qPCR results of mRNA expression levels of related factors. n Western blot analysis of the protein expression level of related factors. o Protein expression levels of related factors. Measurement data were expressed as mean ± standard deviation. Comparisons among multiple groups were conducted by one-way ANOVA followed by Tukey’s post hoc test. *p < 0.05 vs. NC; ^#p < 0.05 vs. Inhibitor NC. The experiment was repeated three times independently