Fig. 2
From: ADAM17 promotes the invasion of hepatocellular carcinoma via upregulation MMP21
ADAM17 promotes the invasion and migration of hepatocellular carcinoma cells. a, b Effects of ADAM17 suppression on cell migration measured by the wound healing assay in SMMC7721 and MHCC97H cells (magnification, × 100). c Quantification of cell closure percentage. d Knockdown of ADAM17 impairs the invasive capacities of SMMC7721 and MHCC97H cells. e Quantification of cell invasion through Matrigel with each cell treatment (***P < 0.001 based on the Mann–Whitney U test). f Overexpression ADAM17 up-regulate invasion ability in Huh7 and SMMC7721 cells (magnification, × 100)