Fig. 4

miR-27a-3p played a tumor suppressive role in GC. a qRT-PCR was utilized to investigate the relative expression of miR-27a-3p in AGS cells transfected with miR-27a-3p mimics and MGC-803 cells with anti-miR-27a-3p. b, c CCK-8 assay and BrdU experiment were utilized to detect the proliferation of GC cells after transfection (scale bar = 20 µm). d Wound healing assay was utilized to investigate the migration of GC cells after transfection. e Transwell assay was utilized to investigate the migration and invasion of MGC-803 and AGS cells after transfection (scale bar = 20 µm). * symbolizes P < 0.05, ** symbolizes P < 0.01, and *** symbolizes P < 0.001