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Table 3 List of the 9 most significant small molecule drugs that can reverse the tumoral status of LSCC

From: Identification and validation of methylation-driven genes prognostic signature for recurrence of laryngeal squamous cell carcinoma by integrated bioinformatics analysis

CMap name Mean N Enrichment P Specificity Percent non-null
Thiocolchicoside − 0.85 4 − 0.837 0.00123 0 100
Gibberellic acid − 0.714 4 − 0.804 0.00284 0.0107 100
Ciclacillin − 0.866 4 − 0.786 0.00422 0.0056 100
Cetirizine − 0.705 4 − 0.781 0.00465 0.0242 100
Medrysone − 0.7 6 − 0.764 0.00032 0.0108 100
Lomefloxacin − 0.655 6 − 0.726 0.00085 0 83
Pramocaine − 0.708 5 − 0.711 0.00435 0 80
Metamizole sodium − 0.695 6 − 0.657 0.00455 0.0684 83
Tolbutamide − 0.566 7 − 0.598 0.00643 0 71