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Fig. 8 | Cancer Cell International

Fig. 8

From: Aging-related tumor associated fibroblasts changes could worsen the prognosis of GBM patients

Fig. 8

Subtype distribution differences showed that higher mesenchymal subtype in patients equal and greater than 40 years old. a Composition charts showed a specific subtype distribution character of mesenchymal and other subtypes among different aged patients. b Patients equal and greater than 40 years old had higher level of mesenchymal subtype than patients equal and greater than 40 years old. Chi-square test was used as statistical method. P = 0.002; c Violin plot showed mesenchymal subtype had higher level of fibroblasts than those of other subtypes. d, e Transwell showed greater migration capacity in patients equal and greater than 40 (≥ 40) years old than those of patients under 40 (< 40) years old. f, g Western blotting assay showed higher expression of mesenchymal markers Vimentin and CD44 and lower expression of epithelial marker E-cadherin in group of equal and greater than 40 (≥ 40) years old than those of patients under 40 (< 40) years old

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