Fig. 3

−14q and resistance to Sunitinib. Reproduced from TCGA, shown were a overall survival, b progression-free survival and c clinicopathological parameters of patient with and without −14q; Gene enrichment and functional annotation analysis in TCGA cases with or without −14q using the d NET-GE and e GSEA platforms; f Reproduced from TCGA dataset, shown was correlation between copy number against corresponding mRNA expression of the gene of interest; g Reproduced from TCGA and Human Protein Atlas dataset, shown was overall survival of patients with higher and lower KLHL33 expression with automatically designated cutoff value; h Reproduced from GEO dataset, shown was KLHL33 expression in Sunitinib –untreated and –resistant RCC cells (Data were presented as mean ± standard deviation; *P < 0.05)