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Fig. 5 | Cancer Cell International

Fig. 5

From: Hsa_circ_0026416 promotes proliferation and migration in colorectal cancer via miR-346/NFIB axis

Fig. 5

Hsa_circ_0026416 promotes CRC progression by a ceRNA pattern in vitro. ad qRT-PCR showing that NFIB and miR-346 are upregulated in HCT-8 and SW480 cells after pcDNA3.1-NFIB, and miR-346 mimics transfection also downregulated expression in HCT-8 and SW480 cells after si-NFIB and miR-346 inhibitor transfection. eh Transwell and CCK-8 assays indicating that pcDNA3.1-NFIB rescues the inhibitory function of miR-346 mimics on migratory, invasive and proliferative activity in HCT-8 and SW480 cells. il Transwell and CCK-8 assays indicating that si-NFIB rescues the enhanced function of miR-346 inhibitor on migratory, invasive and proliferative activity of HCT-8 and SW480 cells. Data are presented as means ± SD of three independent experiments. *P < 0.05, **P < 0.01, *** or ****P < 0.001

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