Fig. 2

Global view of all lncRNAs expression in PCa tissues compared to paired non-PCa tissues. a Boxplot. The medians between samples were roughly flat, and the ranges of expressions were similar. b Sample correlation matrix. The correlation coefficient within the groups was significantly higher than that between the groups, which indicated the larger differences between PCa tissues and paired non-PCa tissues. c Principal component analysis. The difference between normal and tumor was large in the first principal component, but slightly in the second principal component, which showed there was a big difference between the samples. d Hierarchy Clustering Analysis. Repeated samples are clustered together, indicating the repeatability of samples and the differences between samples. The black dotted line divides lncRNAs into two categories: above the line, it presented the part of high expression in non-PCa tissues and low expression in PCa, and below the line, it presented the part of high expression in PCa and low expression in non-PCa tissues. Overall, through a variety of global analysis, we concluded that our tissue samples used in our study presented good reproducibility and the large differences between groups.