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Table 2 Cox regression analysis of PRC1 protein expression and other clinical prognostic factors for overall survival in colon cancer patients (n = 90)

From: Overexpression of protein regulator of cytokinesis 1 facilitates tumor growth and indicates unfavorable prognosis of patients with colon cancer

Factors

HR

Univariate analysis 95% CI

P

HR

Multivariate analysis 95% CI

P

Gender (female/male)

1.439

0.776–2.667

0.248

1.710

0.914–3.201

0.093

Age (≥ 65/ < 65 years)

1.561

0.796–3.060

0.195

1.705

0.861–3.374

0.126

Size of tumor (> 5 cm/ ≤ 5 cm)

2.085

1.112–3.908

0.022*

1.840

0.934–3.626

0.078

Lymph node metastasis (N1–3/N0)

2.550

1.377–4.724

0.003*

2.697

1.432–5.078

0.002*

p-TNM stages (II + III + IV/I)

2.950

1.501–5.800

0.002*

2.393

1.196–4.788

0.014*

PRC1 expression (high/low)

5.853

2.285–14.997

0.000*

4.766

1.840–12.346

0.001*

  1. HR hazard ration, 95% CI 95% confidence interval
  2. * P < 0.05