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Fig. 5 | Cancer Cell International

Fig. 5

From: Spider venom components decrease glioblastoma cell migration and invasion through RhoA-ROCK and Na+/K+-ATPase β2: potential molecular entities to treat invasive brain cancer

Fig. 5

a Purification of F1 and F2 by high – pressure liquid chromatography (HPLC). This procedure generated twelve subfractions, named SF1 to SF12. b Cell viability assay (MTT) performed after 24 h of PnV and SF1-SF12 exposure. The subfractions (1.0 µg/ml) did not induce change in the viability of glioblastoma (NG97) cells viability. Only de crude venom (PnV) induced a decrease, compared to control. All toxins were used at 1.0 μg/ml. PnV (14 μg/ml) promoted a subtle decrease of cell viability (not significant). ***P < 0.001, compared to control. Results of three independent experiments

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Cancer Cell International

ISSN: 1475-2867

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