Fig. 6

XIST silencing suppresses CRC progression via regulation of FOXK1 in vitro. HT29 and SW480 cells were transfected with si-NC, si-XIST, si-XIST + pcDNA, or si-XIST + FOXK1. a Expression of FOXK1 protein was measured by Western blot. b Cell proliferation was analyzed by CCK8 assay. c Cell apoptosis was analyzed using flow cytometry. d, e A transwell assay was used to assess cell migration and invasion abilities. ^*p < 0.05; ^**p < 0.01