Fig. 4
From: ETS1-activated SNHG10 exerts oncogenic functions in glioma via targeting miR-532-3p/FBXL19 axis
FBXL19 was negatively regulated by miR-532-3p. a The expression levels of three predicted mRNAs targeted by miR-532-3p were evaluated via RT-qPCR. b FBXL19 expression was measured by RT-qPCR in cells transfected with NC mimics or miR-532-3p mimics. c, d FBXL19 expression was evaluated by RT-qPCR in cells transfected with sh-SNHG10#1/2 or pcDNA3.1/SNHG10. e Binding sites between FBXL19 and miR-532-3p were shown. f RNA pull down experiments validated that FBXL19 could bind to miR-532-3p. g Luciferase reporter assay certified the influence of miR-532-3p on the luciferase activity of FBXL19-WT/Mut. h RIP validated that SNHG10, miR-532-3p and FBXL19 were co-existed in Ago2-assembled RNA induced silencing complexes (RISCs). *P < 0.05, **P < 0.01, n.s. presented no significance