Fig. 1
From: MiR-4310 induced by SP1 targets PTEN to promote glioma progression
miR-4310 promotes glioma cell proliferation, migration, and invasion by activating PI3K/AKT pathway and promoting EMT progress. a The expression of miR-4310 in NB tissues and glioma tissues were examined by qPCR. b The proliferative ability of indicated U87 and LN229 cells were evaluated by EdU assays; c The cell viability of indicated U87 and LN229 cells were evaluated by MTT assays. d–f The migration ability and invasion ability of U87 and LN229 cells were tested by Transwell assays (d), Boyden assays (e) and wound healing assay (f). g, h The expression of PI3K/AKT pathway and EMT related proteins were examined by Western blot. GAPDH were used as a loading control. Data were presented as mean ± s.d. NS, no statistical significance, *p<0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001