Table 2 Summary of univariate and multivariate Cox regression analysis of overall survival duration. (Data from Nanfang Hospital neurosurgery department)
From: MiR-4310 induced by SP1 targets PTEN to promote glioma progression
Univariate analysis | Multivariate analysis (Forward:LR) | |||||
|---|---|---|---|---|---|---|
p | HR | 95% CI | p | HR | 95% CI | |
Age (years) | ||||||
0–20 | 0.1 | – | – | 0.148 | – | – |
20–50 | 0.046 | 0.309 | 0.097–0.981 | 0.854 | – | – |
50–80 | 0.107 | 0.561 | 0.278–1.133 | 0.082 | – | – |
Gender | 0.585 | 0.846 | 0.464–1.543 | 0.85 | – | – |
Grade | ||||||
WHO I | <0.0001 | – | – | <0.0001 | ||
WHO II | 0.034 | 0.114 | 0.015–0.852 | 0.022 | 0.096 | 0.013–0.717 |
WHO III | <0.0001 | 0.216 | 0.109–0.427 | <0.0001 | 0.134 | 0.062–0.289 |
WHO IV | 0.047 | 0.422 | 0.180–0.988 | 0.022 | 0.359 | 0.150–0.861 |
sp1 | 0.046 | 0.54 | 0.295–0.989 | 0.051 | – | – |
PTEN | 0.134 | 0.635 | 0.350–1.150 | 0.243 | – | – |
miR-4310 | 0.227 | 0.688 | 0.375–1.262 | 0.002 | 0.344 | 0.173–0.684 |