Fig. 4

CDK1 was targeted by miR-148a. a The sequences of miR-148a containing the CDK1 3′UTR binding sites and mutant binding sites were shown. b, c The binding of miR-148a in 3′UTR of CDK1 was verified by dual-luciferase reporter assay. d, e The enrichments of CDK1 and miR-148a in Anti-IgG, Anti-Ago2 and Input were detected by RIP assay. f, g WB analysis was used to detect the effect of miR-148a expression on the protein level of CDK1 in SiHa and Hela cells. *P < 0.05