Fig. 4
From: FABP7 is a potential biomarker to predict response to neoadjuvant chemotherapy for breast cancer
Compared with parental MDA-MB-231, MDA-MB-231-ADR lowly express FABP7 and tend to arrest cell cycle at G0/G1 phase. a The protein level of FABP7 in ER negative and ER positive group. b The mRNA levels of FABP7 in MDA-MB-231, MDA-MB-435, MCF-7, T47D breast cancer cells. c The morphology of MDA-MB-231 and MDA-MB-231-ADR cells. d The cell viability analysis of MDA-MB-231 and MDA-MB-231-ADR cells after treating with doxorubicin. e The mRNA levels of FABP7 and ESR1 in MDA-MB-231 and MDA-MB-231-ADR cells were measured by real-time PCR. f The protein level of FABP7, ESR1, Cdh1, Skp2, p27 were detected by Western blotting analysis in MDA-MB-231 and MDA-MB-231-ADR cells. g The different proportion of DNA in cell cycle in MDA-MB-231 and MDA-MB-231-ADR cells